pluriSpin® Human Monocyte Enrichment, for the negative selection of cells, was developed to isolate a clean, vital and untouched monocyte cell population from whole blood, buffy coat, umbilical cord blood, bone marrow or similar sample materials. The product labels the B cells, T cells, NK cells, granulocytes and leaves the monocyte fraction untouched. By means of a subsequent density gradient centrifugation - PBMC Spin - all labelled cells are removed from the sample together with the erythrocytes (RBC) and the granulocytes. The untouched and unlabeled fraction of monocytes remains enriched together with platelets in the interphase between plasma and density medium.