Positive controls for HemaVision®-7Q and HemaVision®-28Q is an in vitro diagnostic kit containing five identical tubes with in vitro transcribed RNA diluted into wild type leucocyte RNA from the cell line HL60. The in vitro transcribed RNA originates from transcription of 10 fusion gene constructs. These five tubes with of in vitro transcribed RNA mixed with HL60 total RNA can be used as positive controls for the 7 translocations detected by the HemaVision“-7Q kit and 9 of the 28 translocations detected by the HemaVision“-28Q kit. The HL60 RNA contains transcripts of the three housekeeping genes, which are detected by reaction control primers and probe of the HemaVision“ kits.